Amelioration of Experimental autoimmune encephalomyelitis and DSS induced colitis by NTG-A-009 through the inhibition of Th1 and Th17 cells differentiation

CD4(+) T cells are the central for the mammalian adaptive immune system. Naïve CD4(+) T cells mainly differentiate in to pro-inflammatory Th1, Th2 and Th17 cells upon antigenic stimulation. IFN-γ secreting Th1 cells and IL-17 secreting Th17 cells are found to play key roles in autoimmune diseases li...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Acharya, Suman, Timilshina, Maheshwor, Jiang, Liyuan, Neupane, Sabita, Choi, Dong-Young, Park, Sang Won, Lee, Sang Yeul, Jeong, Byeong-Seon, Kim, Jung-Ae, Nam, Tae-gyu, Chang, Jae-Hoon
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2018
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958108/
https://ncbi.nlm.nih.gov/pubmed/29773813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26088-y
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