Discoidin domain receptor 1 kinase activity is required for regulating collagen IV synthesis

Discoidin domain receptor 1 (DDR1) is a receptor tyrosine kinase that binds to and is activated by collagens. DDR1 expression increases following kidney injury and accumulating evidence suggests that it contributes to the progression of injury. To this end, deletion of DDR1 is beneficial in ameliora...

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Pubblicato in:Matrix Biol
Autori principali: Borza, Corina M., Su, Yan, Tran, Truc-Linh, Yu, Ling, Steyns, Nick, Temple, Kayla J., Skwark, Marcin J., Meiler, Jens, Lindsley, Craig W., Hicks, Brennan R., Leitinger, Birgit, Zent, Roy, Pozzi, Ambra
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5329129/
https://ncbi.nlm.nih.gov/pubmed/27915093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2016.11.009
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