Modification of Collagen IV by Glucose or Methylglyoxal Alters Distinct Mesangial Cell Functions

Diabetic nephropathy (DN) affects both glomerular cells and the extracellular matrix (ECM), yet the pathogenic mechanisms involving cell-matrix interactions are poorly understood. Glycation alters integrin-dependent cell-ECM interactions, and perturbation of these interactions results in severe rena...

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Detalhes bibliográficos
Main Authors: Pozzi, Ambra, Zent, Roy, Chetyrkin, Sergei, Borza, Corina, Bulus, Nada, Chuang, Peale, Chen, Dong, Hudson, Billy, Voziyan, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2009
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754111/
https://ncbi.nlm.nih.gov/pubmed/19608705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008080900
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