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Sclerostin expression and functions beyond the osteocyte

Sclerostin, the product of the SOST gene, is a secreted inhibitor of Wnt signaling that is produced by osteocytes to regulate bone formation. While it is often considered an osteocyte-specific protein, SOST expression has been reported in numerous other cell types, including hypertrophic chondrocyte...

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Détails bibliographiques
Publié dans:Bone
Auteurs principaux: Weivoda, Megan M., Youssef, Stephanie J., Oursler, Merry Jo
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328839/
https://ncbi.nlm.nih.gov/pubmed/27888056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.11.024
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