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A Review of Osteocyte Function and the Emerging Importance of Sclerostin

➤ Osteocytes, derived from osteoblasts, reside within bone and communicate extensively with other bone cell populations to regulate bone metabolism. The mature osteocyte expresses the protein sclerostin, a negative regulator of bone mass. ➤ In normal physiologic states, the protein sclerostin acts o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Compton, Jocelyn T., Lee, Francis Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Journal of Bone and Joint Surgery, Inc. 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179450/
https://ncbi.nlm.nih.gov/pubmed/25274791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.M.01096
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