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DIFFERENTIAL ROLE OF BASE EXCISION REPAIR PROTEINS IN MEDIATING CISPLATIN CYTOTOXICITY

Interstrand crosslinks (ICLs) are covalent lesions formed by cisplatin. The mechanism for the processing and removal of ICLs by DNA repair proteins involves nucleotide excision repair (NER), homologous recombination (HR) and fanconi anemia (FA) pathways. In this report, we monitored the processing o...

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Detalles Bibliográficos
Publicado en:DNA Repair (Amst)
Autores principales: Sawant, Akshada, Floyd, Ashley M., Dangeti, Mohan, Lei, Wen, Sobol, Robert W., Patrick, Steve M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328804/
https://ncbi.nlm.nih.gov/pubmed/28110804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.01.002
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