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DIFFERENTIAL ROLE OF BASE EXCISION REPAIR PROTEINS IN MEDIATING CISPLATIN CYTOTOXICITY

Interstrand crosslinks (ICLs) are covalent lesions formed by cisplatin. The mechanism for the processing and removal of ICLs by DNA repair proteins involves nucleotide excision repair (NER), homologous recombination (HR) and fanconi anemia (FA) pathways. In this report, we monitored the processing o...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:DNA Repair (Amst)
Päätekijät: Sawant, Akshada, Floyd, Ashley M., Dangeti, Mohan, Lei, Wen, Sobol, Robert W., Patrick, Steve M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328804/
https://ncbi.nlm.nih.gov/pubmed/28110804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.01.002
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