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ROLE OF MISMATCH REPAIR PROTEINS IN THE PROCESSING OF CISPLATIN INTERSTRAND CROSS-LINKS

Mismatch repair (MMR) deficiency gives rise to cisplatin resistance and can lead to poor prognosis in cancers. Various models have been proposed to explain this low level of resistance caused due to loss of MMR proteins. We have shown that MMR proteins are required to maintain cisplatin interstrand...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Sawant, Akshada, Kothandapani, Anbarasi, Zhitkovich, Anatoly, Sobol, Robert W., Patrick, Steve M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651805/
https://ncbi.nlm.nih.gov/pubmed/26519826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.10.003
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