Glycogen Synthase Kinase-3β Haploinsufficiency Mimics the Behavioral and Molecular Effects of Lithium

Lithium is widely used to treat bipolar disorder, but its mechanism of action in this disorder is unknown. Several molecular targets of lithium have been identified, but these putative targets have not been shown to be responsible for the behavioral effects of lithium in vivo. A robust model for the...

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Bibliographic Details
Published in:J Neurosci
Main Authors: O'Brien, W. Timothy, Harper, Amber DeAra, Jové, Fernando, Woodgett, James R., Maretto, Silvia, Piccolo, Stefano, Klein, Peter S.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2004
Subjects:
Behavioral/Systems/Cognitive
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328671/
https://ncbi.nlm.nih.gov/pubmed/15282284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4753-03.2004
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