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Glycogen Synthase Kinase-3β Haploinsufficiency Mimics the Behavioral and Molecular Effects of Lithium

Lithium is widely used to treat bipolar disorder, but its mechanism of action in this disorder is unknown. Several molecular targets of lithium have been identified, but these putative targets have not been shown to be responsible for the behavioral effects of lithium in vivo. A robust model for the...

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Pubblicato in:J Neurosci
Autori principali: O'Brien, W. Timothy, Harper, Amber DeAra, Jové, Fernando, Woodgett, James R., Maretto, Silvia, Piccolo, Stefano, Klein, Peter S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328671/
https://ncbi.nlm.nih.gov/pubmed/15282284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4753-03.2004
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