Antidiabetic and vasoprotective activity of lithium: Role of glycogen synthase kinase-3

OBJECTIVES: Lithium is a drug of choice in maniac disorder. Lithium inhibits the glycogen synthase kinase-3 (GSK-3), an enzyme involved in the insulin signalling pathway. Elevated levels of GSK-3 were found in diabetic rats and humans. We aimed to determine the effect of lithium chloride in diabetes...

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Bibliographic Details
Main Authors: Kanzariya, Nilesh R., Patel, Rameshvar K., Patel, Natvar J.
Format: Artigo
Language:Inglês
Published: Medknow Publications 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153708/
https://ncbi.nlm.nih.gov/pubmed/21845000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0253-7613.83116
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