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Ciprofloxacin-Mediated Mutagenesis Is Suppressed by Subinhibitory Concentrations of Amikacin in Pseudomonas aeruginosa

Resistance to antibiotics is a global health problem. Activation of the SOS response, and the subsequent elevation in mutagenesis, contributes to the appearance of resistance mutations. Among currently used drugs, quinolones are the most potent inducers of the SOS response. In the present study, we...

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Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Valencia, Estela Ynés, Esposito, Fernanda, Spira, Beny, Blázquez, Jesús, Galhardo, Rodrigo S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328548/
https://ncbi.nlm.nih.gov/pubmed/28031197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02107-16
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