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Ciprofloxacin-Mediated Mutagenesis Is Suppressed by Subinhibitory Concentrations of Amikacin in Pseudomonas aeruginosa

Resistance to antibiotics is a global health problem. Activation of the SOS response, and the subsequent elevation in mutagenesis, contributes to the appearance of resistance mutations. Among currently used drugs, quinolones are the most potent inducers of the SOS response. In the present study, we...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Valencia, Estela Ynés, Esposito, Fernanda, Spira, Beny, Blázquez, Jesús, Galhardo, Rodrigo S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328548/
https://ncbi.nlm.nih.gov/pubmed/28031197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02107-16
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