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Ciprofloxacin-Mediated Mutagenesis Is Suppressed by Subinhibitory Concentrations of Amikacin in Pseudomonas aeruginosa

Resistance to antibiotics is a global health problem. Activation of the SOS response, and the subsequent elevation in mutagenesis, contributes to the appearance of resistance mutations. Among currently used drugs, quinolones are the most potent inducers of the SOS response. In the present study, we...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Valencia, Estela Ynés, Esposito, Fernanda, Spira, Beny, Blázquez, Jesús, Galhardo, Rodrigo S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328548/
https://ncbi.nlm.nih.gov/pubmed/28031197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02107-16
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