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Ciprofloxacin-Mediated Mutagenesis Is Suppressed by Subinhibitory Concentrations of Amikacin in Pseudomonas aeruginosa

Resistance to antibiotics is a global health problem. Activation of the SOS response, and the subsequent elevation in mutagenesis, contributes to the appearance of resistance mutations. Among currently used drugs, quinolones are the most potent inducers of the SOS response. In the present study, we...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Valencia, Estela Ynés, Esposito, Fernanda, Spira, Beny, Blázquez, Jesús, Galhardo, Rodrigo S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328548/
https://ncbi.nlm.nih.gov/pubmed/28031197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02107-16
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