Anastrozole in Pulmonary Arterial Hypertension. A Randomized, Double-Blind, Placebo-controlled Trial

Rationale: The aromatase inhibitor anastrozole blocks the conversion of androgens to estrogen and blunts pulmonary hypertension in animals, but its efficacy in treating patients with pulmonary arterial hypertension (PAH) is unknown. Objectives: We aimed to determine the safety and efficacy of anastr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Am J Respir Crit Care Med
Hauptverfasser: Kawut, Steven M., Archer-Chicko, Christine L., DeMichele, Angela, Fritz, Jason S., Klinger, James R., Ky, Bonnie, Palevsky, Harold I., Palmisciano, Amy J., Patel, Mamta, Pinder, Diane, Propert, Kathleen J., Smith, K. Akaya, Stanczyk, Frank, Tracy, Russell, Vaidya, Anjali, Whittenhall, Mary E., Ventetuolo, Corey E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2017
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328182/
https://ncbi.nlm.nih.gov/pubmed/27602993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201605-1024OC
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge