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Are Hemodynamics Surrogate Endpoints in Pulmonary Arterial Hypertension?

BACKGROUND: While frequently assessed in trials and clinical practice, hemodynamic response to therapy has never been validated as a surrogate endpoint for clinical events in pulmonary arterial hypertension (PAH). METHODS AND RESULTS: We performed a patient-level pooled analysis of four randomized p...

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Detalhes bibliográficos
Main Authors: Ventetuolo, Corey E., Gabler, Nicole B., Fritz, Jason S., Smith, K. Akaya, Palevsky, Harold I., Klinger, James R., Halpern, Scott D., Kawut, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146736/
https://ncbi.nlm.nih.gov/pubmed/24951771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.009690
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