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Anastrozole in Pulmonary Arterial Hypertension. A Randomized, Double-Blind, Placebo-controlled Trial

Rationale: The aromatase inhibitor anastrozole blocks the conversion of androgens to estrogen and blunts pulmonary hypertension in animals, but its efficacy in treating patients with pulmonary arterial hypertension (PAH) is unknown. Objectives: We aimed to determine the safety and efficacy of anastr...

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Bibliografiske detaljer
Udgivet i:Am J Respir Crit Care Med
Main Authors: Kawut, Steven M., Archer-Chicko, Christine L., DeMichele, Angela, Fritz, Jason S., Klinger, James R., Ky, Bonnie, Palevsky, Harold I., Palmisciano, Amy J., Patel, Mamta, Pinder, Diane, Propert, Kathleen J., Smith, K. Akaya, Stanczyk, Frank, Tracy, Russell, Vaidya, Anjali, Whittenhall, Mary E., Ventetuolo, Corey E.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328182/
https://ncbi.nlm.nih.gov/pubmed/27602993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201605-1024OC
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