Effect of simvastatin on MMPs and TIMPs in cigarette smoke-induced rat COPD model

BACKGROUND: Proteases may play an important role in the development of chronic obstructive pulmonary disease and emphysema in response to cigarette smoke exposure (CSE). The current study was designed to investigate the expression of matrix metalloproteinase (MMP)-8, MMP-9, MMP-12, tissue inhibitor...

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Bibliografiske detaljer
Udgivet i:Int J Chron Obstruct Pulmon Dis
Main Authors: Sun, Jiawei, Bao, Jie, Shi, Yanan, Zhang, Bin, Yuan, Lindong, Li, Junhong, Zhang, Lihai, Sun, Mo, Zhang, Ling, Sun, Wuzhuang
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327908/
https://ncbi.nlm.nih.gov/pubmed/28260878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S110520
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