Effect of simvastatin on MMPs and TIMPs in cigarette smoke-induced rat COPD model

BACKGROUND: Proteases may play an important role in the development of chronic obstructive pulmonary disease and emphysema in response to cigarette smoke exposure (CSE). The current study was designed to investigate the expression of matrix metalloproteinase (MMP)-8, MMP-9, MMP-12, tissue inhibitor...

Full description

Saved in:
Bibliographic Details
Published in:Int J Chron Obstruct Pulmon Dis
Main Authors: Sun, Jiawei, Bao, Jie, Shi, Yanan, Zhang, Bin, Yuan, Lindong, Li, Junhong, Zhang, Lihai, Sun, Mo, Zhang, Ling, Sun, Wuzhuang
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2017
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327908/
https://ncbi.nlm.nih.gov/pubmed/28260878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S110520
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items