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Simvastatin mitigates functional and structural impairment of lung and right ventricle in a rat model of cigarette smoke-induced COPD

Objectives: This study is conducted to investigate an effect of simvastatin on cigarette smoke-induced COPD. Methods: Rats were exposed to air (control) and cigarette smoke (smoking) in presence and absence of simvastatin. Heart and lung tissues were harvested for histopathologic and morphometric an...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Wang, Yajie, Jiang, Xue, Zhang, Lihai, Wang, Lihong, Li, Zhu, Sun, Wuzhuang
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314029/
https://ncbi.nlm.nih.gov/pubmed/25674219
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