Effect of simvastatin on MMPs and TIMPs in cigarette smoke-induced rat COPD model

BACKGROUND: Proteases may play an important role in the development of chronic obstructive pulmonary disease and emphysema in response to cigarette smoke exposure (CSE). The current study was designed to investigate the expression of matrix metalloproteinase (MMP)-8, MMP-9, MMP-12, tissue inhibitor...

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Detalhes bibliográficos
Publicado no:Int J Chron Obstruct Pulmon Dis
Main Authors: Sun, Jiawei, Bao, Jie, Shi, Yanan, Zhang, Bin, Yuan, Lindong, Li, Junhong, Zhang, Lihai, Sun, Mo, Zhang, Ling, Sun, Wuzhuang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327908/
https://ncbi.nlm.nih.gov/pubmed/28260878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S110520
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