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Transcription factor family‐specific DNA shape readout revealed by quantitative specificity models
Transcription factors (TFs) achieve DNA‐binding specificity through contacts with functional groups of bases (base readout) and readout of structural properties of the double helix (shape readout). Currently, it remains unclear whether DNA shape readout is utilized by only a few selected TF families...
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| Publié dans: | Mol Syst Biol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5327724/ https://ncbi.nlm.nih.gov/pubmed/28167566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20167238 |
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