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Massively parallel single nucleotide mutagenesis using reversibly-terminated inosine
Large-scale mutagenesis of target DNA sequences comprehensively assesses the effects of single nucleotide changes. Here we demonstrate the construction of a systematic allelic series (SAS) using massively parallel single nucleotide mutagenesis with reversibly-terminated deoxyinosine triphosphates (r...
Gorde:
| Argitaratua izan da: | Nat Methods |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5327618/ https://ncbi.nlm.nih.gov/pubmed/27694911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4015 |
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