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Exploring the role of PGC-1α in defining nuclear organisation in skeletal muscle fibres

Muscle fibres are multinucleated cells, with each nucleus controlling the protein synthesis in a finite volume of cytoplasm termed the myonuclear domain (MND). What determines MND size remains unclear. In the present study, we aimed to test the hypothesis that the level of expression of the transcri...

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Pubblicato in:J Cell Physiol
Autori principali: Ross, Jacob A., Pearson, Adam, Levy, Yotam, Cardel, Bettina, Handschin, Christoph, Ochala, Julien
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326684/
https://ncbi.nlm.nih.gov/pubmed/27861863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25678
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