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Exploring the role of PGC-1α in defining nuclear organisation in skeletal muscle fibres

Muscle fibres are multinucleated cells, with each nucleus controlling the protein synthesis in a finite volume of cytoplasm termed the myonuclear domain (MND). What determines MND size remains unclear. In the present study, we aimed to test the hypothesis that the level of expression of the transcri...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Ross, Jacob A., Pearson, Adam, Levy, Yotam, Cardel, Bettina, Handschin, Christoph, Ochala, Julien
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326684/
https://ncbi.nlm.nih.gov/pubmed/27861863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25678
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