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Skeletal muscle PGC-1α modulates systemic ketone body homeostasis and ameliorates diabetic hyperketonemia in mice

Ketone bodies are crucial energy substrates during states of low carbohydrate availability. However, an aberrant regulation of ketone body homeostasis can lead to complications such as diabetic ketoacidosis. Exercise and diabetes affect systemic ketone body homeostasis, but the regulation of ketone...

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Bibliografske podrobnosti
izdano v:FASEB J
Main Authors: Svensson, Kristoffer, Albert, Verena, Cardel, Bettina, Salatino, Silvia, Handschin, Christoph
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970654/
https://ncbi.nlm.nih.gov/pubmed/26849960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201500128
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