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PGC-1β-expressing POMC neurons mediate the effect of leptin on thermoregulation in the mouse

The arcuate nucleus (ARC) of the hypothalamus is a key regulator of food intake, brown adipose tissue (BAT) thermogenesis, and locomotor activity. Whole-body deficiency of the transcriptional coactivator peroxisome proliferator-activated receptor γ (PPARγ) coactivator-1β (PGC-1β) disrupts mouse circ...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Delezie, Julien, Gill, Jonathan F., Santos, Gesa, Karrer-Cardel, Bettina, Handschin, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567876/
https://ncbi.nlm.nih.gov/pubmed/33060645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73794-7
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