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Sirolimus therapy is associated with elevation in circulating PCSK9 levels in cardiac transplant patients

Sirolimus used in transplantation is often associated with hypercholesterolemia. We measured serum lipid and PCSK9 levels in 51 heart transplant recipients who had their immunosuppressive therapy switched from calcineurin inhibitors to sirolimus. The switch resulted in a 23% increase in LDL choleste...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Cardiovasc Transl Res
Päätekijät: Simha, Vinaya, Qin, Sisi, Shah, Pankaj, Smith, Byron H., Kremers, Walter K., Kushwaha, Sudhir, Wang, Liewei, Pereira, Naveen L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325778/
https://ncbi.nlm.nih.gov/pubmed/28028691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-016-9719-8
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