Sirolimus affects cardiomyocytes to reduce left ventricular mass in heart transplant recipients

AIMS: The cellular mechanisms underlying cardiac hypertrophy may result from changes in cardiac myocyte growth and differentiation. We tested whether sirolimus, an immunosuppressive agent that inhibits mTOR, a protein that regulates cell division and differentiation, might modify cardiac hypertrophy...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Kushwaha, Sudhir S., Raichlin, Eugenia, Sheinin, Yuri, Kremers, Walter K., Chandrasekaran, Krishnaswamy, Brunn, Gregory J., Platt, Jeffrey L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
Clinical Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721707/
https://ncbi.nlm.nih.gov/pubmed/18790727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehn407
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky