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Isolation and characterization of the circulating truncated form of PCSK9

Proprotein convertase subtilisin-kexin type 9 (PCSK9) is a secreted protein which regulates serum LDL cholesterol. It circulates in human and rodent serum in an intact form and a major truncated form. Previous in vitro studies involving the expression of human PCSK9 genetic variants and in vivo stud...

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Detalles Bibliográficos
Main Authors: Han, Bomie, Eacho, Patrick I., Knierman, Michael D., Troutt, Jason S., Konrad, Robert J., Yu, Xiaohong, Schroeder, Krista M.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076096/
https://ncbi.nlm.nih.gov/pubmed/24776539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M049346
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