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Influence of physiological changes in endogenous estrogen on circulating PCSK9 and LDL cholesterol

Pharmacologically increased estrogen levels have been shown to lower hepatic and plasma proprotein convertase subtilisin/kexin type 9 (PCSK9) levels in animals and humans. We hypothesized that physiological changes in estrogen levels influence circulating PCSK9, thereby contributing to the known wid...

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Bibliographic Details
Published in:J Lipid Res
Main Authors: Ghosh, Moumita, Gälman, Cecilia, Rudling, Mats, Angelin, Bo
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306699/
https://ncbi.nlm.nih.gov/pubmed/25535288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M055780
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