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Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans

Reduced plasma LDL-cholesterol is a hallmark of hyperthyroidism and is caused by transcriptional stimulation of LDL receptors in the liver. Here, we investigated whether thyroid hormone (TH) actions involve other mechanisms that may also account for the reduction in LDL-cholesterol, including effect...

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Detalles Bibliográficos
Publicado en:J Lipid Res
Main Authors: Bonde, Ylva, Breuer, Olof, Lütjohann, Dieter, Sjöberg, Stefan, Angelin, Bo, Rudling, Mats
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617142/
https://ncbi.nlm.nih.gov/pubmed/25172631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M051664
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