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Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans

Reduced plasma LDL-cholesterol is a hallmark of hyperthyroidism and is caused by transcriptional stimulation of LDL receptors in the liver. Here, we investigated whether thyroid hormone (TH) actions involve other mechanisms that may also account for the reduction in LDL-cholesterol, including effect...

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Bibliografski detalji
Izdano u:J Lipid Res
Glavni autori: Bonde, Ylva, Breuer, Olof, Lütjohann, Dieter, Sjöberg, Stefan, Angelin, Bo, Rudling, Mats
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617142/
https://ncbi.nlm.nih.gov/pubmed/25172631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M051664
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