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Sirolimus therapy is associated with elevation in circulating PCSK9 levels in cardiac transplant patients
Sirolimus used in transplantation is often associated with hypercholesterolemia. We measured serum lipid and PCSK9 levels in 51 heart transplant recipients who had their immunosuppressive therapy switched from calcineurin inhibitors to sirolimus. The switch resulted in a 23% increase in LDL choleste...
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| Publicado en: | J Cardiovasc Transl Res |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5325778/ https://ncbi.nlm.nih.gov/pubmed/28028691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-016-9719-8 |
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