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HSP90 shapes the consequences of human genetic variation
HSP90 acts as a protein-folding buffer that shapes the manifestations of genetic variation in model organisms. Whether HSP90 influences the consequences of mutations in humans, potentially modifying the clinical course of genetic diseases, remains unknown. Mining data for >1,500 disease-causing m...
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| 出版年: | Cell |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5325763/ https://ncbi.nlm.nih.gov/pubmed/28215707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.01.023 |
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