Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes

BACKGROUND: Malignant peripheral nerve sheath tumor (MPNST) is an aggressive sarcoma with few treatment options. Tumor immune state has not been characterized in MPNST, and is important in determining response to immune checkpoint blockade. Our aim was to evaluate the expression of programmed death-...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shurell, Elizabeth, Singh, Arun S., Crompton, Joseph G., Jensen, Sarah, Li, Yunfeng, Dry, Sarah, Nelson, Scott, Chmielowski, Bartosz, Bernthal, Nicholas, Federman, Noah, Tumeh, Paul, Eilber, Fritz C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325443/
https://ncbi.nlm.nih.gov/pubmed/27588404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11734
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