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The effect of epigenetic silencing and TP53 mutation on the expression of DLL4 in human cancer stem disorder

The Li-Fraumeni Syndrome (LFS), a genetically rare heterogeneous cancer syndrome, is characterized primarily by a germline p53 (TP53) gene mutation. We recently discovered a balanced reciprocal chromosomal translocation t(11;15)(q23;q15) in the non-cancerous skin fibroblasts of a bilateral breast ca...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Yao, Zhixing, Sherif, Zaki A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325341/
https://ncbi.nlm.nih.gov/pubmed/27542210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11316
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