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DNA Methylation Activates TP73 Expression in Hepatocellular Carcinoma and Gastrointestinal Cancer

The complexity of TP73 expression and its functionality, as well as the role of TP73 in tumorigenesis, unlike its cousin TP53, which is an established tumor suppressor, have remained elusive to date. In this study, we isolated two stem cell lines (HepCY & HepCO) from normal young and old human l...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Yao, Zhixing, Di Poto, Cristina, Mavodza, Grace, Oliver, Everett, Ressom, Habtom W., Sherif, Zaki A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920427/
https://ncbi.nlm.nih.gov/pubmed/31852961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55945-7
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