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DNA Methylation Activates TP73 Expression in Hepatocellular Carcinoma and Gastrointestinal Cancer

The complexity of TP73 expression and its functionality, as well as the role of TP73 in tumorigenesis, unlike its cousin TP53, which is an established tumor suppressor, have remained elusive to date. In this study, we isolated two stem cell lines (HepCY & HepCO) from normal young and old human l...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Yao, Zhixing, Di Poto, Cristina, Mavodza, Grace, Oliver, Everett, Ressom, Habtom W., Sherif, Zaki A.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920427/
https://ncbi.nlm.nih.gov/pubmed/31852961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55945-7
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