Chargement en cours...

Chemoproteomic profiling and discovery of protein electrophiles in human cells

Activity-based protein profiling (ABPP) serves as a chemical proteomic platform to discover and characterize functional amino acids in proteins on the basis of their enhanced reactivity towards small-molecule probes. This approach, to date, has mainly targeted nucleophilic functional groups, such as...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nat Chem
Auteurs principaux: Matthews, Megan L, He, Lin, Horning, Benjamin D, Olson, Erika J, Correia, Bruno E, Yates, John R, Dawson, Philip E, Cravatt, Benjamin F
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325178/
https://ncbi.nlm.nih.gov/pubmed/28221344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2645
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!