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Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes

Sulfonyl-triazoles are a new class of electrophiles that mediate covalent reaction with tyrosine residues on proteins through sulfur-triazole exchange (SuTEx) chemistry. Recent studies demonstrate the broad utility and tunability of SuTEx chemistry for chemical proteomics and protein ligand discover...

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Detalhes bibliográficos
Publicado no:Chem Sci
Principais autores: Huang, Tao, Hosseinibarkooie, Seyyedmohsen, Borne, Adam L., Granade, Mitchell E., Brulet, Jeffrey W., Harris, Thurl E., Ferris, Heather A., Hsu, Ku-Lung
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179411/
https://ncbi.nlm.nih.gov/pubmed/34164099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc06623k
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