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Chemoproteomic Discovery of a Ritanserin-Targeted Kinase Network Mediating Apoptotic Cell Death of Lung Tumor Cells
Ritanserin was tested in the clinic as a serotonin receptor inverse agonist but recently emerged as a novel kinase inhibitor with potential applications in cancer. Here, we discovered that ritanserin induced apoptotic cell death of non–small cell lung cancer (NSCLC) and small cell lung cancer (SCLC)...
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| Publicado no: | Mol Pharmacol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6160665/ https://ncbi.nlm.nih.gov/pubmed/30158316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.118.113001 |
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