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Chemical Stabilization of Unnatural Nucleotide Triphosphates for the in vivo Expansion of the Genetic Alphabet
We have developed an unnatural base pair (UBP) and a semi-synthetic organism (SSO) that imports the constituent unnatural nucleoside triphosphates and uses them to replicate DNA containing the UBP. However, propagation of the UBP is at least in part limited by the stability of the unnatural triphosp...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5325089/ https://ncbi.nlm.nih.gov/pubmed/28170246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b12731 |
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