Regulator of G Protein Signaling 6 Protects the Heart from Ischemic Injury

Gαi-coupled receptors play important roles in protecting the heart from ischemic injury. Regulator of G protein signaling (RGS) proteins suppress Gαi signaling by accelerating the GTPase activity of Gαi subunits. However, the roles of individual RGS proteins in modulating ischemic injury are unknown...

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Vydáno v:J Pharmacol Exp Ther
Hlavní autoři: Rorabaugh, Boyd R., Chakravarti, Bandana, Mabe, Nathaniel W., Seeley, Sarah L., Bui, Albert D., Yang, Jianqi, Watts, Stephanie W., Neubig, Richard R., Fisher, Rory A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2017
Témata:
Cardiovascular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325075/
https://ncbi.nlm.nih.gov/pubmed/28035008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.238345
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