Essentiality of Regulator of G Protein Signaling 6 and Oxidized Ca(2+)/Calmodulin‐Dependent Protein Kinase II in Notch Signaling and Cardiovascular Development

BACKGROUND: Congenital heart defects are the most common birth defects worldwide. Although defective Notch signaling is the major cause of mouse embryonic death from cardiovascular defects, how Notch signaling is regulated during embryonic vasculogenesis and heart development is poorly understood. M...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Chakravarti, Bandana, Yang, Jianqi, Ahlers‐Dannen, Katelin E., Luo, Zili, Flaherty, Heather A., Meyerholz, David K., Anderson, Mark E., Fisher, Rory A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721783/
https://ncbi.nlm.nih.gov/pubmed/29079565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.007038
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