RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation

Urinary bladder cancer (UBC) is largely caused by exposure to toxic chemicals including those in cigarette smoke (i.e. BBN). An activating SNP in RGS6 is associated with a pronounced reduction in UBC risk, especially among smokers. However, the mechanism underlying this reduction remains unknown. He...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yang, Jianqi, Platt, Lance T., Maity, Biswanath, Ahlers, Katelin E., Luo, Zili, Lin, Zhibo, Chakravarti, Bandana, Ibeawuchi, Stella-Rita, Askeland, Ryan W., Bondaruk, Jolanta, Czerniak, Bogdan A., Fisher, Rory A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342467/
https://ncbi.nlm.nih.gov/pubmed/27713144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12473
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados