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Pathogen-mediated inhibition of anorexia promotes host survival and transmission
Sickness-induced anorexia is a conserved behavior induced during infections. Here, we report that an intestinal pathogen, Salmonella Typhimurium, inhibits anorexia by manipulating the gut-brain axis. Inhibition of inflammasome activation by the S. Typhimurium effector, SlrP, prevented anorexia cause...
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| 出版年: | Cell |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5324724/ https://ncbi.nlm.nih.gov/pubmed/28129542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.01.006 |
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