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Pathogen-mediated inhibition of anorexia promotes host survival and transmission
Sickness-induced anorexia is a conserved behavior induced during infections. Here, we report that an intestinal pathogen, Salmonella Typhimurium, inhibits anorexia by manipulating the gut-brain axis. Inhibition of inflammasome activation by the S. Typhimurium effector, SlrP, prevented anorexia cause...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5324724/ https://ncbi.nlm.nih.gov/pubmed/28129542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.01.006 |
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