Pathogen-mediated inhibition of anorexia promotes host survival and transmission

Sickness-induced anorexia is a conserved behavior induced during infections. Here, we report that an intestinal pathogen, Salmonella Typhimurium, inhibits anorexia by manipulating the gut-brain axis. Inhibition of inflammasome activation by the S. Typhimurium effector, SlrP, prevented anorexia cause...

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Bibliografische gegevens
Gepubliceerd in:Cell
Hoofdauteurs: Rao, Sheila, Palaferri Schieber, Alexandria M., O’Connor, Carolyn P., Leblanc, Mathias, Michel, Daniela, Ayres, Janelle S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324724/
https://ncbi.nlm.nih.gov/pubmed/28129542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.01.006
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