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Disease tolerance mediated by commensal E. coli via inflammasome and IGF-1 signaling
Infections and inflammation can lead to cachexia and wasting of skeletal muscle and fat tissue by as yet poorly understood mechanisms. We observed that gut colonization of mice by a strain of Escherichia coli prevents wasting triggered by infections or physical damage to the intestine. During intest...
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| Publié dans: | Science |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4732872/ https://ncbi.nlm.nih.gov/pubmed/26516283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac6468 |
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