Cooperative metabolic adaptations in the host can favor asymptomatic infection and select for attenuated virulence in an enteric pathogen

Pathogen virulence exists on a continuum. The strategies that drive symptomatic or asymptomatic infections remain largely unknown. We took advantage of the concept of lethal dose 50 (LD50) to ask which component of individual non-genetic variation between hosts defines whether they survive or succum...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell
Prif Awduron: Sanchez, Karina K., Chen, Grischa Y., Schieber, Alexandria M. Palaferri, Redford, Samuel E., Shokhirev, Maxim N., Leblanc, Mathias, Lee, Yujung M., Ayres, Janelle S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447043/
https://ncbi.nlm.nih.gov/pubmed/30100182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.07.016
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