Effect of Food on the Bioavailability of Omadacycline in Healthy Participants

Omadacycline is a first‐in‐class aminomethylcycline antibiotic being evaluated in phase 3 studies as oral and intravenous monotherapy for bacterial infections. This was a phase 1, randomized, open‐label, 4‐period, crossover study that evaluated the effect of food consumption on the bioavailability o...

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Vydáno v:J Clin Pharmacol
Hlavní autoři: Tzanis, Evan, Manley, Amy, Villano, Stephen, Tanaka, S. Ken, Bai, Stephen, Loh, Evan
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Pharmacokinetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324643/
https://ncbi.nlm.nih.gov/pubmed/27539539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.814
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